Last year's beaten finalists Wexford will face Roscommon in the semi-finals of the TG4 All-Ireland Intermediate Championship while Clare take on Laois.
Eight games are down for decision on live television across the All-Ireland senior and minor championship knockout stages, and the All-Ireland ladies senior championship group phase.
Eighty club sides from Ireland, the UK, Europe and the US will compete in the John West Féile na nGael National Camogie and Hurling Finals 2022 across ten venues in Dublin and Meath on Saturday.
Tyrone will clash with last year's beaten TG4 All-Ireland Intermediate Championship finalists Wexford in the pick of the quarter-finals this time around.
There's a feast of live GAA action this weekend; eight teams vying for four All-Ireland SFC quarter-final spots and there's All-Ireland SHC preliminaries taking place in Belfast and Tralee.
Niall McNamee and his cousin Ruairi McNamee pointed the way for Offaly as John Maughan's men moved into the Tailteann Cup quarter-finals with a 0-18 to 0-10 defeat of Wicklow at O'Connor Park in Tullamore this afternoon.
Aisling Murphy scored both goals as last year's beaten finalists Wexford began the 2022 TG4 All-Ireland Intermediate Championship with a 2-12 to 3-7 victory over Offaly.
The draw for the quarter finals of the GAA's Tailteann Cup senior football competition will take place next Monday morning and will be made live on Morning Ireland on RTÉ Radio 1 at 8.35am.
The final pieces of silverware in the 2022 TG4 Provincial Championships will be handed out on Saturday - before attention switches on Sunday to the start of the TG4 All-Ireland Championships.
The new second tier All-Ireland senior football championship officially got underway this afternoon with Wicklow defeating Waterford 3-16 to 1-10 at Aughrim.
Today's hurling fixtures see silverware and final places up for grabs as Wicklow and Waterford meet in the opening game of the inaugural Tailteann Cup.